通过Metagene集群和预测模型绘制肿瘤Immune地貌图

Pan-Cancer Mapping of the Tumor Immune Landscape through Metagene Clustering and Predictive Modeling

As immunotherapies become standard cancer treatments, it is increasingly important to identify a patient's immune profile, which encompasses the activity of immune cells within the tumor microenvironment and the presence of specific biomarkers. However, we lack mechanistic explanations drivers of immune phenotypes. Despite advances in immune profiling with high-throughput sequencing, the mechanisms driving them remain unclear. This study aimed to identify novel, robust immune-related gene cluste