Geodia cydonium, a sponge belonging to Demospongiae and endemic species to the Mediterranean Sea, is capturing increasing attention due to its rich and chemically diverse metabolome. Previous studies ...
Natural products from marine and terrestrial organisms provide an important resource for medicinal chemistry and drug discovery. Defined as occurring at depths greater than 200 m, most of the ocean, b...
1. Marine organisms have fascinated scientists with their unique and unparalleled biodiversity and therapeutic potential.2. They are known to possess novel bioactive compounds with varied pharmacologi...
In recent years, Marine Natural Products (MNPs) have emerged as a significant source for anticancer drug discovery, as many natural products can offer structural diversity, unique mechanisms of action...
Marine-derived Streptomyces are among the most prolific producers of structurally diverse and biologically active natural products. Adaptation to unique marine environments, including deep-sea sedimen...
Current computational approaches for drug design typically focus on generating molecules conditioned on specific targets or general molecular properties, often neglecting the influence of disease cont...
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