Financial markets are often modelled as if time were unique and continuous across assets and markets. Financial markets are however asynchronous, order flow is event-driven, and waiting times between ...
Bridging the gap between animal and human experiments remains a major challenge in translational medicine, particularly in early drug development. Progress is constrained by financial cost, the diffic...
The Wasserstein median is a robust alternative to the Wasserstein barycenter for averaging probability measures, but exact empirical computation can be expensive. A natural metric-space Weiszfeld sche...
The Teissier distribution, originally proposed by Teissier [31], was designed to model mortality due to aging in domestic animals. More recently, Krishna et al. [19] introduced the Unit Teissier (UT) ...
We introduce Hyper Input Convex Neural Networks (HyCNNs), a novel neural network architecture designed for learning convex functions. HyCNNs combine the principles of Maxout networks with input convex...
Stochastic approximation (SA) is a fundamental iterative framework with broad applications in reinforcement learning and optimization. Classical analyses typically rely on martingale difference or Mar...
Efficient sampling of molecular systems at thermodynamic equilibrium is a hallmark challenge in statistical physics. This challenge has driven the development of Boltzmann Generators (BGs), which allo...
We propose a method for summarizing multiple solutions to SEIR-type compartmental models on a functional space by computing a constrained power Fréchet mean with functional registration to obtain cons...
High-resolution brain imaging can now capture not just synapse locations but their molecular composition, with the cost of such mapping falling exponentially. Yet such ultrastructural data has so far ...
Neuromorphic computing is closely associated with spiking neuronal networks. However, an alternative class of so-called "rate-based" models arising from computational neuroscience and machine learning...
System prompts are instructions configured by developers to govern the behaviors of foundation models in AI applications. They are used throughout commercial AI products, but are rarely disclosed to t...
Background: Pleuroparenchymal fibroelastosis (PPFE) is an upper lobe predominant fibrotic lung abnormality associated with increased mortality in established interstitial lung disease. However, the cl...
Multilevel network meta-regression (ML-NMR) enables population-adjusted indirect treatment comparisons by combining individual patient data (IPD) with aggregate data. When individual-level covariates ...
Modern imaging instruments can produce terabytes to petabytes of data for a single experiment. The biggest barrier to processing big image datasets has been computational, where image analysis algorit...
Building virtual cells with generative models to simulate cellular behavior in silico is emerging as a promising paradigm for accelerating drug discovery. However, prior image-based generative approac...
Cardiac digital twin research is moving from subject-specific anatomical replicas toward virtual cohorts that represent clinically relevant population subgroups. Yet access to representative imaging-d...
The ranking of recommendation algorithms is a challenging problem since model performance is sensitive to dataset characteristics such as sparsity, sequential structure, and scale. This drives a deman...
Quantum machine learning is a promising paradigm for learning from limited data, a central bottleneck in domains such as medical imaging, clinical trials, and rare diseases. Quantum convolutional neur...
Ocean acidification (OA) driven by increasing atmospheric CO2 is altering marine biodiversity. However, impacts of OA on ecosystem functioning at the community level, including calcification, primary ...
Marine biosecurity stands at the crossroads of innovation and necessity, with artificial intelligence (AI) offering promising tools to enhance risk assessment, surveillance, and response strategies fo...