Bacterial cancer therapy exploits anaerobic bacteria's ability to target hypoxia tumor regions, yet the interactions among tumor growth, bacterial colonization, oxygen levels, immunosuppressive cytoki...
Microbial interaction networks can rewire in response to host and environmental factors, yet most existing methods for network estimation treat the covariance structure as static across samples. We pr...
Single-cell molecular characterization remains a bottleneck in scalable biological analysis because of labeling requirements, limited multiplexing, and reagents that perturb physiology. Raman spectros...
Raman spectroscopy is a promising tool for microbial identification, yet its implementation in microbiology and clinical workflow is still restricted due to the accompanying additional preparation req...
Experimental and theoretical studies of circadian rhythms have focused largely on the period, on mutants that alter it and on phase shifts, and this focus has driven the identification of clock genes ...
Ramkrishna, Kompala, and Tsao proposed the cybernetic model of microbial growth, in which cells allocate enzyme synthesis resources according to a matching rule that mimics rational decision-making. T...
With the intensified exploration of marine resources, marine bioactive peptides have become one of the research focuses in biomedicine, food science, and materials science because of their structural ...
Microbe-mineral interactions play a crucial role in microbial energy conservation and mineral mobilization within deep-sea hydrothermal vents, yet the specific microorganisms involved remain largely u...
Marine organisms from deep-sea environments have attracted considerable attention in drug discovery because they produce structurally diverse natural products. However, Norwegian deep-sea ecosystems r...
For the bioremediation of contaminated sites, the efficiency of bioaugmentation depends on the survival capacity of introduced degradative strains in environmental settings. Many isolated strains exhi...
The reductive citric acid (rTCA) and reverse oxidative TCA (roTCA) cycles are used by autotrophic Bacteria to fix dissolved inorganic carbon (DIC) at deep-sea and terrestrial hot springs, water treatm...
The genus Psychromonas includes psychrophilic or psychrotolerant bacteria frequently isolated from cold marine environments, such as polar regions, the deep sea and cold currents, however, its taxonom...
Antarctic marine food webs are expected to be significantly impacted by future climate change. In particular, the recent rapid regional warming in the West Antarctic Peninsula has, and will continue t...
Marine fungal natural products are valuable sources of structurally diverse and biologically active compounds with potential applications in drug discovery and biotechnology. The fungus Penicillium cr...
Microbial phytases are crucial to organic phosphorus mineralization in marine phosphorus cycle, however, phytases from deep-sea bacteria remain poorly characterized. Here, we isolated and cultured a p...
Hydrothermal systems contain diverse alkanes derived from biological and geological processes, providing potential carbon and energy sources for microorganisms. However, cultivated thermophilic alkane...
Microbial degradation represents a promising remediation strategy for polyvinyl chloride (PVC) and polycarbonate (PC) microplastics, which have been widely detected in the Haima cold seeps. However, t...
Heterotrophic bacteria process a large fraction of the polysaccharides produced by phytoplankton in the surface ocean. Some of these polysaccharides are taken up by "selfish" bacteria, which bind, par...
Iron is one of the most important elements of the Earth, yet its bioavailability is limited in oceanic environments. In this context, deep-sea hydrothermal ecosystems represent one of the major source...
The hadal zone presents one of the most extreme environments on Earth. While amphipods dominate this realm, the adaptive mechanisms of their resident gut microbiota are not fully understood, which is ...