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A structurally novel exopolysaccharide DSP-1 from the deep-sea-derived fungus Didymella keratinophila with potent immunostimulatory activity.

Recently marine fungal polysaccharides have attracted increasing attention and interest; however, most reported sources originate from shallow or coastal environments, and knowledge regarding those de...

👤 Hou Qili, Chen Xinye, Zhong Cheng, Li Ya... 📰 Chemico-Biological Interactions 📅 2026 👁 91 📚 10

Chemical constituents and ferroptosis inhibitory activity of the deep-sea-derived fungus Penicillium citrinum W24.

One new citrinin derivative (1) and one new fatty acid (27) were isolated from the marine Penicillium citrinum W24, together with 29 known compounds. Their structures were determined by extensive spec...

👤 Lin Cheng-You, Wang Yuan, Wu Tai-Zong, C... 📰 Natural Product Research 📅 2026 👁 70 📚 10

Novel prenylated diketopiperazines with anti-osteoclastogenic activity from the deep-sea-derived Penicillium limosum ZEN48.

A systematic chemical investigation of the deep-sea-derived fungus Penicillium limosum ZEN48 resulted in the isolation of four new indole-diketopiperazine alkaloids, limopiperazines A-D (1-4), alongsi...

👤 Zhang Yong, Guo Yan-Qing, Li You, Zou Zh... 📰 未知期刊 📅 2026 👁 50 📚 10

Chemical Constituents of Deep-Sea-Derived Fungus Penicillium citrinum W17 and Their Ferroptosis Inhibitory Activity.

Two new polyketides (1-2) were isolated from the deep-sea-derived fungus Penicillium citrinum W17, along with 39 known compounds (3-41). The structures were established by 1D and 2D NMR, HRESIMS data ...

👤 Zhang A-Long, Zou Zheng-Biao, Guo Yan-Qi... 📰 Chemistry & Biodiversity 📅 2026 👁 91 📚 9

Chemical Constituents of the Deep-Sea-Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity.

Deep-sea-derived fungi have emerged as a prolific source of structurally novel and pharmacologically active secondary metabolites, representing an invaluable reservoir of lead compounds for drug disco...

👤 Ma Ke-Xin, Zou Zheng-Biao, Wu Qi-Qian, L... 📰 未知期刊 📅 2026 👁 62 📚 9

Drimane-Pyrone-Type Meroterpenoids and Co-Isolated Compounds from the Deep-Sea Fungus Penicillium rubens MABC05 and Their Anti-Ferroptotic and Cytotoxic Activities.

Ferroptosis is a critical driver of tubular necrosis, and its effective inhibition holds significant potential for mitigating renal injury. In this study, chemical investigation of the strain Penicill...

👤 Liu Lingyan, Yang Xinjia, Hu Caixia, Wan... 📰 未知期刊 📅 2026 👁 28 📚 3

The Greenland shark genome: Insights into lifespan extremes and population dynamics.

The Greenland shark (Somniosus microcephalus) is known for its slow metabolism and deep-sea habitat. It is thought to be the longest-lived vertebrate on Earth, with an estimated lifespan of 392 ± 120 ...

👤 Yang Kaiqiao, Nishiwaki Kazuya, Mizobata... 📰 Proceedings of the National Academy of Sciences 📅 2026 👁 60 📚 1
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