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Genome Mining of Deep-Sea Cold Seep-Derived Fungus Reveals a Laccase-Fasciclin System Modulating Regioselective Naphthopyranone Dimerization.

Naphthopyranones represent a structurally diverse family of fungal polyketides exhibiting a broad range of biological activities, including antibacterial, antifungal, and cytotoxic properties. Despite...