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Interpretable enzyme function prediction via sparse autoencoder features of ESMC across the microbial protein universe

Microbial genomes and metagenomes contain millions of proteins whose enzymatic functions remain unknown, the enzyme dark matter. While deep learning has improved protein function prediction, most meth...

👤 Yue Hu | Wanyu Cheng | Junqing Wang | Yi... 📰 arXiv 📅 2026 👁 191 📚 9

Phylogenomic and metabolic insights into iron reduction metabolism in the genus Deferribacter belonging to the order Deferribacterales.

Iron is one of the most important elements of the Earth, yet its bioavailability is limited in oceanic environments. In this context, deep-sea hydrothermal ecosystems represent one of the major source...

👤 Pouder Eva, Alain Karine, Mieszkin Sophi... 📰 Microbial Genomics 📅 2026 👁 59 📚 9

Metagenomic Insights Into Red Sea Biodiversity Across the Web of Life.

Earth's biodiversity is central to ecosystem health and resilience, providing essential functions and services. The Red Sea is a recognised marine biodiversity hotspot with high endemism and unique en...

👤 Laiolo Elisa, Hempel Christopher A, Abuk... 📰 未知期刊 📅 2026 👁 52 📚 9

Sulphur metabolism as a key factor in the evolution of environmental adaptation of Acidihalobacter.

This study compares predicted sulphur metabolism genes across four Acidihalobacter type strains and two metagenome-assembled genomes (MAGs), revealing genomic differences that appear to correspond to ...

👤 Vergara Eva, Khaleque Himel Nahreen, Nei... 📰 Microbial Genomics 📅 2026 👁 44 📚 8

Electrosynthetic bacterial growth under conditions simulating electric discharge in deep-sea hydrothermal fields.

Microbial electrosynthesis is a metabolic process in which extracellular electrons are utilized as the primary energy source for carbon fixation. While microbial electrosynthesis has been proposed as ...

👤 Masukawa Hinako, Kobayashi Runa, Watanab... 📰 未知期刊 📅 2026 👁 43 📚 8

Unveiling active microbial processes in Earth's deepest seawater.

Microorganisms dominate life in the hadal zone, yet extreme sampling difficulty and low biomass have precluded characterization of their in situ activities. Here, we analyze microbiome samples collect...

👤 Zhang Wei-Jia, Hu Aoran, Wu Ziheng, Liu ... 📰 未知期刊 📅 2026 👁 32 📚 7

Vertical distribution and metabolic diversity of autotrophic microbes in the deep sediment of the challenger deep.

Carbon fixation in marine ecosystems is a vital process that contributes to climate regulation, with ocean sediments playing a critical role in carbon sequestration. This process is driven by chemolit...

👤 Zhou Jiahua, Cheng Haojin, Zhang Yulin, ... 📰 Environmental Microbiome 📅 2026 👁 55 📚 5

Multi-Omic Assessment of Microbial Communities and Their Polyketide Biosynthetic Potential Across Abyssal Sediments.

Microbially-derived polyketides include some of today's most valuable medicines, yet their discovery has focused on a narrow subset of Earth's microbial biodiversity. Although understudied biomes such...

👤 Singh Hans W, Gutleben Johanna, Bogdanov... 📰 Environmental Microbiology 📅 2026 👁 45 📚 4

Evidence for the connectivity of antibiotic resistance genes between seamount and coastal environments.

Antibiotic resistance genes (ARGs) have drawn global attention and are ubiquitously detected in marine environments. Seamounts, prominent seafloor features with high biodiversity, may be hotspots for ...

👤 Guo Nairong, Chen Jiahao, Lei Zhenyuan, ... 📰 Ecotoxicology and Environmental Safety 📅 2026 👁 41 📚 4

Methanotrophic community structure and metabolic potential in the sulfate-methane transition zone of the ARAON mounds, Arctic Chukchi Sea.

Anaerobic oxidation of methane (AOM) mediated by archaea is a pivotal process for methane consumption in gas seepage-associated sediments. Despite its importance in regulating methane flux, the ecolog...

👤 Jeon Jehyun, Lee Dong-Hun, Kim Ji-Hoon, ... 📰 Marine Environmental Research 📅 2026 👁 63 📚 3

From microbial diversity to functional potential using dimensionality reduction.

The high dimensionality of microbial diversity data from 'omics observations can be reduced using Machine Learning, with many recent studies showcasing ML utility for exploratory ecological feature fi...

👤 Chamberlain Emelia J, Boulton William, C... 📰 未知期刊 📅 2026 👁 52 📚 2

A deep-sea rare bacterium exhibits extraordinary metabolic versatility.

The rare biosphere harbors immense microbial diversity, yet most low-abundance taxa remain uncultured and functionally enigmatic. Here, we isolated strain D14T from deep-sea water, and propose to clas...

👤 Li Zhimeng, Chi Baihui, Ruan Chujin, Son... 📰 未知期刊 📅 2026 👁 50 📚 2

Infection Dynamics and Coexistence of Two Novel Arctic Phytoplankton Viruses.

Marine algal viruses exhibit a high level of diversity, and closely related viruses targeting the same algal host species can stably coexist. Here we report an example of a single virus-host system co...

👤 Meyer Claudia, Jackson Victoria L N, de ... 📰 未知期刊 📅 2026 👁 33 📚 1

Water mass specific genes dominate the Southern Ocean microbiome.

The Southern Ocean (SO) plays a key role in regulating global biogeochemical cycles and climate, yet microbial genes sustaining its biological activity remain poorly characterized. We introduce a micr...

👤 Faure Emile, Pommellec Jolann, Noel Cyri... 📰 Nature Communications 📅 2026 👁 57 📚 0

TPMM: Three-component Posterior Mixture Model Enables Robust Inverton Detection in Low-Depth Metagenomes and Suggests Potential Viral Invertons

Bacterial phase variation enables reversible, locus-specific phenotypic switching, often driven by DNA inversion (invertons). To identify these events, researchers commonly rely on sequencing reads th...

👤 未知 📰 arXiv 📅 - 👁 36 📚 0

Metagenomic analysis of water column samples collected from Green Canyon 233 prior to the Deepwater Horizon incident.

The Gulf of Mexico/Gulf of America provides ecosystem services derived from marine biodiversity and oil and gas resources. Threats posed by unintended releases of oil and gas can be attenuated by micr...

👤 Lim Shen Jean, Thompson Luke R, Goodwin ... 📰 未知期刊 📅 2026 👁 17 📚 0
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