Bacterial cancer therapy exploits anaerobic bacteria's ability to target hypoxia tumor regions, yet the interactions among tumor growth, bacterial colonization, oxygen levels, immunosuppressive cytoki...
How external stimulation is transformed into distributed reaction patterns remains unresolved at the level of propagation architecture. Existing large-scale control models quantify transition costs on...
Alkaptonuria (AKU) is an ultra-rare autosomal recessive metabolic disorder caused by mutations in the HGD (Homogentisate 1,2-Dioxygenase) gene, leading to a pathological accumulation of homogentisic a...
We propose and analyze an optimal control problem associated with a Keller-Segel type parabolic system with chemoattraction, modeling the glioblastoma growth in a bi-dimensional bounded domain, influe...
The Arctic Ocean plays a pivotal role in global climate, yet its circulation under greenhouse conditions remains poorly constrained. Seismic, sedimentological, and drilling evidence from the Chukchi S...
Global superanoxia is widely accepted as one of the main drivers of the end–Permian Mass Extinction (EPME) alongside, oceanic acidification, productivity collapse, and toxification. However, modeling ...
Sulfur is a redox active element that may have helped mediate an electron flow that kickstarted life and which presently is an essential element for all life on Earth. Despite current uncertainties in...
The rise of atmospheric oxygen fundamentally transformed Earth's surface environment and enabled the evolution of complex life. However, the processes driving long-term oxygen fluctuations remain poor...
The evolution of El Niño-Southern Oscillation (ENSO) under past and future climate change and its influence on marine ecosystems is highly debated. To examine links between tropical climate variabilit...
Seamount ecosystems are increasingly exposed to rapid oceanographic change, including warming waters, declining oxygen concentrations, and the upward migration of carbonate saturation horizons. Togeth...
