Two new polyketides (1-2) were isolated from the deep-sea-derived fungus Penicillium citrinum W17, along with 39 known compounds (3-41). The structures were established by 1D and 2D NMR, HRESIMS data ...
Microbially-derived polyketides include some of today's most valuable medicines, yet their discovery has focused on a narrow subset of Earth's microbial biodiversity. Although understudied biomes such...
Geodia cydonium, a sponge belonging to Demospongiae and endemic species to the Mediterranean Sea, is capturing increasing attention due to its rich and chemically diverse metabolome. Previous studies ...
Natural products from marine and terrestrial organisms provide an important resource for medicinal chemistry and drug discovery. Defined as occurring at depths greater than 200 m, most of the ocean, b...
In recent years, Marine Natural Products (MNPs) have emerged as a significant source for anticancer drug discovery, as many natural products can offer structural diversity, unique mechanisms of action...
Naphthopyranones represent a structurally diverse family of fungal polyketides exhibiting a broad range of biological activities, including antibacterial, antifungal, and cytotoxic properties. Despite...
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