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Chemical Constituents of Deep-Sea-Derived Fungus Penicillium citrinum W17 and Their Ferroptosis Inhibitory Activity.

Two new polyketides (1-2) were isolated from the deep-sea-derived fungus Penicillium citrinum W17, along with 39 known compounds (3-41). The structures were established by 1D and 2D NMR, HRESIMS data ...

👤 Zhang A-Long, Zou Zheng-Biao, Guo Yan-Qi... 📰 Chemistry & Biodiversity 📅 2026 👁 60 📚 9

Multi-Omic Assessment of Microbial Communities and Their Polyketide Biosynthetic Potential Across Abyssal Sediments.

Microbially-derived polyketides include some of today's most valuable medicines, yet their discovery has focused on a narrow subset of Earth's microbial biodiversity. Although understudied biomes such...

👤 Singh Hans W, Gutleben Johanna, Bogdanov... 📰 Environmental Microbiology 📅 2026 👁 35 📚 4

Biological and chemical investigation of metabolites from the marine sponge Geodia cydonium (Linnaeus, 1767) methanolic extract against melanoma cancer cell lines.

Geodia cydonium, a sponge belonging to Demospongiae and endemic species to the Mediterranean Sea, is capturing increasing attention due to its rich and chemically diverse metabolome. Previous studies ...

👤 Federico Serena, Esposito Roberta, De Ro... 📰 Natural Product Research 📅 2026 👁 37 📚 3

Marine Natural Products as Potent Anticancer Agents (2020-2024): Structural Diversity, SARs and Target Prediction.

In recent years, Marine Natural Products (MNPs) have emerged as a significant source for anticancer drug discovery, as many natural products can offer structural diversity, unique mechanisms of action...

👤 Huang Zimeng, Du Yijing, Hu Junzhe, Ying... 📰 Marine Drugs 📅 2026 👁 40 📚 1

Genome Mining of Deep-Sea Cold Seep-Derived Fungus Reveals a Laccase-Fasciclin System Modulating Regioselective Naphthopyranone Dimerization.

Naphthopyranones represent a structurally diverse family of fungal polyketides exhibiting a broad range of biological activities, including antibacterial, antifungal, and cytotoxic properties. Despite...

👤 Li Hongcheng, Li Zhiting, Sun Junpeng, Y... 📰 International Journal of Molecular Sciences 📅 2026 👁 51 📚 0
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