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Prior-informed conditional Gaussian graphical models: an application to protein interaction network reconstruction

Protein-protein interaction (PPI) networks, estimated from high-throughput omics data, foster biomarker discovery and precision medicine. Gaussian graphical models (GGMs) offer a principled reconstruc...

👤 Alessia Mapelli | Michela Carlotta Massi... 📰 arXiv 📅 2026 👁 214 📚 22

The Identification of Biological Stains at Crime Scenes: A Promising Role for Proteomics and Machine Learning

Forensic body fluid identification is crucial for reconstructing crime scene events. While DNA analysis provides individualization, it lacks information about the fluid's origin. We developed and eval...

👤 Anna Rosenberg | Stéphanie Laurent | Est... 📰 arXiv 📅 2026 👁 73 📚 22

Advancing the Resolution of the Sulfur Compound Disproportionation Puzzle in Dissulfuribacter Thermophilus S69ᵀ Through Quantitative Label-Free Comparative Proteomics.

In deep-sea hydrothermal vents, sulfur compounds are central for microbial bioenergetics. Despite its significant impact on the global sulfur cycle, anaerobic sulfur compound disproportionation remain...

👤 Fernandez Marilina, Schoepp-Cothenet Bar... 📰 未知期刊 📅 2026 👁 69 📚 9

Valid Inference with Synthetic Data via Task Exchangeability

There is a proliferation of work arguing for the use of synthetic data in scientific research. For example, social scientists are arguing for the use of LLM-generated "silicon samples" in pilot studie...

👤 Lezhi Tan | Tijana Zrnic 📰 arXiv 📅 2026 👁 206 📚 6

Anti-Neuroinflammatory Naphtho-γ-Pyrones from a Deep-Sea-Derived Fungus Aspergillus niger 3A00562.

Inhibition of inflammation and oxidative stress is increasingly recognized as a promising therapeutic strategy for neurodegenerative diseases. In this study, we isolated two new dimeric naphtho-γ-pyro...

👤 Xu Zi-Han, Zou Zheng-Biao, Wang Chun-Xiu... 📰 Marine Drugs 📅 2026 👁 42 📚 6
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