Aspertetranones are a unique class of marine fungal meroditerpenoids characterized by a highly oxygenated, linear 6/6/6/6 tetracyclic core fused to an α-pyrone scaffold. Although the pathway of aspert...
Fungal polyisoprenylated benzophenones typically exhibit potent biological activities. In our previous research, a series of novel polyisoprenylated benzophenones, namely lithocarols A-F, were discove...
Three previously undescribed GABA-containing heptapeptides, named unguisins P-R (1-3), were obtained from the deep-sea-derived fungus Aspergillus candidus SCSIO 41234. Their structures were elucidated...
Inhibition of inflammation and oxidative stress is increasingly recognized as a promising therapeutic strategy for neurodegenerative diseases. In this study, we isolated two new dimeric naphtho-γ-pyro...
One new fatty acid derivative (3Z,5E)-8-(hydroxymethyl)-2-(3-methoxy-2-methyl-3-oxopropyl)-4,6,10,12-tetramethyltetradeca-2,4-dienoic acid (1) and fifteen known compounds 2-16 were isolated from the A...
Deep-sea extreme environments harbor microorganisms with unique adaptive mechanisms. Fungi play significant ecological roles in these ecosystems, yet the regulatory pathways governing their adaptation...
Fungal infections are a significant contributor to global morbidity and mortality, among which Candida albicans infections, a major cause of systemic candidiasis, have a mortality rate of approximatel...
Two new anthraquinone derivatives, (±)-1'-O-methyl-6-chloroaverantin (1a and 1b) and 6-chloroaverythrin (2), and one new diphenyl ether 1-((E)-but-2-en-2-yl)-3,8-dihydroxy-6-((E)-4-hydroxybut-2-en-2-y...
Naphthopyranones represent a structurally diverse family of fungal polyketides exhibiting a broad range of biological activities, including antibacterial, antifungal, and cytotoxic properties. Despite...
🌊
