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Anti-Neuroinflammatory Naphtho-γ-Pyrones from a Deep-Sea-Derived Fungus Aspergillus niger 3A00562.

Inhibition of inflammation and oxidative stress is increasingly recognized as a promising therapeutic strategy for neurodegenerative diseases. In this study, we isolated two new dimeric naphtho-γ-pyro...

👤 Xu Zi-Han, Zou Zheng-Biao, Wang Chun-Xiu... 📰 Marine Drugs 📅 2026 👁 21 📚 6

A new fatty acid derivative derived from the deep-sea fungus Aspergillus sp. SCSIO41324.

One new fatty acid derivative (3Z,5E)-8-(hydroxymethyl)-2-(3-methoxy-2-methyl-3-oxopropyl)-4,6,10,12-tetramethyltetradeca-2,4-dienoic acid (1) and fifteen known compounds 2-16 were isolated from the A...

👤 Chen Yu-Shi, Song Ying-Ying, Deng Sheng-... 📰 未知期刊 📅 2026 👁 44 📚 4

Discovery and evaluation of a marine-derived chlorinated flavone derivative CHNQD-02204 as a potent and selective antifungal agent against Candida albicans.

Fungal infections are a significant contributor to global morbidity and mortality, among which Candida albicans infections, a major cause of systemic candidiasis, have a mortality rate of approximatel...

👤 Cao Xi-Zhen, Wang Cui-Fang, Guo Jin-Zhou... 📰 European Journal of Medicinal Chemistry 📅 2026 👁 73 📚 3

New Cytotoxic Anthraquinone Derivatives from a Deep-Sea-Derived Aspergillus sp. SCSIO 41331.

Two new anthraquinone derivatives, (±)-1'-O-methyl-6-chloroaverantin (1a and 1b) and 6-chloroaverythrin (2), and one new diphenyl ether 1-((E)-but-2-en-2-yl)-3,8-dihydroxy-6-((E)-4-hydroxybut-2-en-2-y...

👤 Wu Ziyi, Zheng Zehan, Zhong Weimao, Jian... 📰 未知期刊 📅 2026 👁 41 📚 2

Genome Mining of Deep-Sea Cold Seep-Derived Fungus Reveals a Laccase-Fasciclin System Modulating Regioselective Naphthopyranone Dimerization.

Naphthopyranones represent a structurally diverse family of fungal polyketides exhibiting a broad range of biological activities, including antibacterial, antifungal, and cytotoxic properties. Despite...

👤 Li Hongcheng, Li Zhiting, Sun Junpeng, Y... 📰 International Journal of Molecular Sciences 📅 2026 👁 50 📚 0
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